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Establishment of State Biotech. Hub(SBT Hub) in Sikkim

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Establishment of State Biotech Hub (SBT Hub) in Sikkim

About the Project

The project “Establishment of State BioTech. Hubs (SBT Hubs) in Sikkim” is funded by Department of Biotechnology (DBT), Govt. of India under a special programme for North Eastern States. It is coordinated by Biotech Consortium India Limited (BCIL), a Government of India enterprise. The project includes establishing state-of-the-art biotechnology infrastructure and a nucleus research centre. Total cost: Rs. 304.03 lakhs. Duration: 3 years.
Objectives:
1. To promote Biotechnology and allied science in the state of Sikkim through R & D, training and awareness activities.
2. Development of trained human resources; promote entrepreneurship in the field of biotechnology and allied field.
3. To identify and work in the area that will helps to improve the socio-economic condition of the people through the application of biotechnology and allied technology.
4. To undertake research and explore the prospect to solve the current the environmental, food, healthcare problems of state through the application of biotechnology and allied technology.
5. To work in tandems with the State Government policy and intervene on the areas which can assist in successful implementation of its policy.
Goals:
I. Undertake research on new product development; explore the solution of current problems of crops, environment, and healthcare through the application of biotechnology.
Generate maximum awareness especially amongst students, teachers and researchers to inculcate interest in the field of biotechnology.
Setting-up of Biotechnology Incubation Centre in Sikkim for entrepreneurs’ with the financial support of Government of India and State Government.
Setting-up of Biotech labs in science labs of Senior Secondary Schools with the support of Department of Biotechnology, Government of India under BLISS programme.
Setting-up of Regional Biotechnology Research and Training Institute in Sikkim.
Generation of job oriented trained and skilled human resources in the field of biotechnology and allied field.

Project Objectives

  • Establish biotechnology infrastructure in the state
  • Train coordinators of institutional hubs
  • Support research and training
  • Establish linkage with other institutional hubs in the state

Procurement of Scientific Equipment

S. No. Name of Equipment Model No. & Brand
1 Incubator shaker Innova 44, New Brunswick scientific, USA
2 Bio-Spectrophotometer basic Eppendorf, USA

Training Conducted

  • Training on Molecular biology techniques (20.09.2013) with 150 participants
  • Training on antioxidant, plant tissue culture, antimicrobial studies to Science PG students of Sikkim University (5 students)

Research Activities

Sl. No. Title of the Research Status
1Antioxidant profiling of Curcuma angustifolia by DPPH method.Accepted: IJLBPR (ISSN 2250-3137)
2Antioxidant profiling of medicinal plants Hippophae salicifolia by DPPH methodCommunicated
3Isolation of spores from Citrus reticulata roots soil samplesCommunicated
4Antimicrobial, antioxidant, phytochemical study of Vaccinium sikkimenseCommunicated
5Molecular studies on 15 varieties of Sechium sp.Ongoing
6Micropropagation protocol for Stevia rebaudiana & Asparagus racemosusOngoing
7Micropropagation of Bambusa nutans & genetic diversity in Sikkim HimalayaOngoing
8In vitro propagation and molecular studies of Musa paradisiaca varietiesOngoing
9In vitro propagation & antioxidant study of Rattan speciesOngoing
10Phylogenetic studies of 36 Rhododendron speciesOngoing
11Documentation of medicinal plants used for diabetes in West SikkimCommunicated: Journal of Indian Traditional Knowledge
12Seabuckthorn - A Secret Wonder Species: ReviewAccepted: SMU Medical Journal
13Rattan - Neglected Climbing Tree - An OverviewCommunicated
14In vitro antibacterial, antioxidant activity of 5 ginger cultivarsAccepted: International Food Research Journal
15Micropropagation of Amomum subulatumPublished: IJLBPR (April 2014)
16Genetic diversity of 5 ginger cultivars using RAPDPublished: SMU Medical Journal (Jan 2014)

Additional Activities

  • Creation of germplasm for cardamom and ginger
  • Addition of more herbal plants in garden
  • Outreach to science students from different schools
  • Support for Sikkim Govt. College Biotech Hub establishment
  • Member participation in institutional hub committees at SGC, Gangtok
  • Technical and programmatic support to biotech hubs around Gangtok

Other Activities

Sl. No Name of Programme
1 Hands on training to the coordinators of institutional hubs on molecular biology techniques, plant tissue culture, anti-oxidants, pollen & anther culture.
2 Hands on training to the science post graduate teacher on basic molecular biology techniques.
3 Strengthening of laboratory with necessary instruments to carry out various researches.
4 Training to the post graduate science students on basic laboratory techniques and molecular biology.
5 Taking PhD students from this year.
6 Development of polyploid large cardamom, pure line selection for breeding and development of disease/drought resistant hybrid.
7 Pollen genomic studies of Rhododendron species of Sikkim Himalaya.
8 Bio-prospecting of local medicinal plants.

Publication of Biotech Hub

Sl. No Publication Details Impact Factor
1 Talambedu Usha, Sushen Pradhan, Arvind Kumar Goyal, Bharat Chandra Basistha, Sushil Kumar Middha et al. (2017). Molecular Simulation-based Combinatorial Modeling and Antioxidant Activities of Zingibereceae Family Rhizomes, Pharmacogn Mag. 13(3), 715-722. 1.7
2 Amrit Kumar Panda, Satpal Sigh Bisht, Bodh Raj Kaushal, Surajit De Mandal, Nachi muthu Senthil Kumar and Bharat C. Basistha (2017). Bacterial diversity analysis of Yumthang hot spring, North Sikkim, India by Illumina sequencing, Big Data Analytics, 2,7. -
3 Swastika Gurung, Veena Pande, Faristha Yasmi, B.C. Basistha (2017). Algal diversity in the sacred lake of Tung Kyoung, Dzongu, Northern Sikkim, Phykos. 47(2), 95-99. -
4 Pratima Ghimiray, B.C Basistha, K. K. Biswas, Veena Pande (2018). Incidence And Molecular Diagnosis Of Citrus Tristeza Virus In Mandarin (Citrus Reticulata) Orchards Of Sikkim, CIBTech Journal of Biotechnology, 7(1), 1-7. -
5 Sushil Middha, Talambedu Usha, Bharat Basistha, Arvind Kr. Goyal (2019). Amelioration of Antioxidant potential, toxicity and anti-hyperglycemic activity of Hippophae salicifolia D. Don leaf extracts in alloxan-induced diabetic rats. 3Biotech 09:308. -


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